TY - JOUR
T1 - Harnessing cognitive neuroscience to develop new treatments for improving cognition in schizophrenia
T2 - CNTRICS selected cognitive paradigms for animal models
AU - Moore, Holly
AU - Geyer, Mark A.
AU - Carter, Cameron S.
AU - Barch, Deanna M.
N1 - Funding Information:
CNTRICS was funded by National Institutes of Health Grant 1R13MH078710 .
PY - 2013/11
Y1 - 2013/11
N2 - Over the past two decades, the awareness of the disabling and treatment-refractory effects of impaired cognition in schizophrenia has increased dramatically. In response to this still unmet need in the treatment of schizophrenia, the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative was developed. The goal of CNTRICS is to harness cognitive neuro-science to develop a brain-based set of tools for measuring cognition in schizophrenia and to test new treatments. CNTRICS meetings focused on development of tasks with cognitive construct validity for use in both human and animal model studies. This special issue presents papers discussing the cognitive test-ing paradigms selected by CNTRICS for animal model systems. These paradigms are designed to measure cognitive constructs within the domains of perception, attention, executive function, working memory, object/relational long-term memory, and social/affective processes.
AB - Over the past two decades, the awareness of the disabling and treatment-refractory effects of impaired cognition in schizophrenia has increased dramatically. In response to this still unmet need in the treatment of schizophrenia, the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative was developed. The goal of CNTRICS is to harness cognitive neuro-science to develop a brain-based set of tools for measuring cognition in schizophrenia and to test new treatments. CNTRICS meetings focused on development of tasks with cognitive construct validity for use in both human and animal model studies. This special issue presents papers discussing the cognitive test-ing paradigms selected by CNTRICS for animal model systems. These paradigms are designed to measure cognitive constructs within the domains of perception, attention, executive function, working memory, object/relational long-term memory, and social/affective processes.
UR - http://www.scopus.com/inward/record.url?scp=84888835568&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2013.09.011
DO - 10.1016/j.neubiorev.2013.09.011
M3 - Editorial
C2 - 24090823
AN - SCOPUS:84888835568
SN - 0149-7634
VL - 37
SP - 2087
EP - 2091
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
IS - 9
ER -