GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture

Keyphrases

• GWAS Analysis 100%
• Genetic Architecture 100%
• Subtype-specific 100%
• Locus-specific 100%
• Risk Loci 100%
• People with Epilepsy 100%
• Genetic Generalized Epilepsy 100%
• Epilepsy 66%
• Genome-wide Association Study 33%
• Inhibitory Neurons 33%
• Excitatory Neurons 33%
• Current Treatment 33%
• Common Variants 33%
• Genetic Risk 33%
• Epilepsy Genetics 33%
• Heritable Disorders 33%
• Repurposing 33%
• SNP Heritability 33%
• Causal Genes 33%
• Generalized Epilepsy 33%
• Epilepsy Treatment 33%
• Subtype Analysis 33%
• Gene Analysis 33%
• Multi-ancestry 33%
• Focal Epilepsy 33%
• Heritability Analysis 33%
• Antiseizure Medication 33%
• Synaptic Processes 33%
• Monogenic Epilepsies 33%
• Gene Overlapping 33%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Genome Wide Association Study 100%
• Genetic Architecture 100%
• Genome-Wide Association Study 33%
• Candidate Gene 33%
• Single Nucleotide Polymorphism 33%
• Genetic Risk 33%
• Overlapping Gene 33%

Neuroscience

• Meta-Analysis 100%
• Genetic Generalized Epilepsy 100%
• Genome-Wide Association Study 33%
• Antiseizure Medication 33%
• Generalised Epilepsy 33%
• Overlapping Gene 33%