TY - JOUR
T1 - Graphical interpretation and analysis of proteins and their ontologies (GiaPronto)
T2 - A one-click graph visualization software for proteomics data sets
AU - Weiner, Amber K.
AU - Sidoli, Simone
AU - Diskin, Sharon J.
AU - Garcia, Benjamin A.
N1 - Funding Information:
* This work was supported by NIH grants R01GM110174 and P01CA196539, and DOD grant W81XWH-113-1-0426. BAG also acknowledges funding from the Leukemia and Lymphoma Society Dr. Robert Arceci Scholar Award. This work was supported by a grant from the W.W. Smith Charitable Trust (SJD). We have declared no conflict of interest. ‖ To whom correspondence should be addressed: Genomics and Computational Biology, Biomedical Graduate Studies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104. Tel.: 215-573-9423; Email: [email protected]. edu.
Publisher Copyright:
© 2018 Andrade-Silva et al. Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.
PY - 2018/7
Y1 - 2018/7
N2 - Here we present a free interactive web tool to process and visualize proteomics data sets with a single click. GiaPronto can process all proteomics quantification methods, i.e. label-free, SILAC and isobaric labeling, and analyze post-translational modifications (PTMs). The software performs normalization and statistics, assists determination of regulated proteins, biomarkers and Gene Ontology (GO) enrichment, and provides high resolution images and tables for further data analysis. We foresee that GiaPronto will become the most rapid and simple tool for assessing data quality and determining most relevant features of proteomic data sets. GiaPronto is available at giapronto.diskinlab.org.
AB - Here we present a free interactive web tool to process and visualize proteomics data sets with a single click. GiaPronto can process all proteomics quantification methods, i.e. label-free, SILAC and isobaric labeling, and analyze post-translational modifications (PTMs). The software performs normalization and statistics, assists determination of regulated proteins, biomarkers and Gene Ontology (GO) enrichment, and provides high resolution images and tables for further data analysis. We foresee that GiaPronto will become the most rapid and simple tool for assessing data quality and determining most relevant features of proteomic data sets. GiaPronto is available at giapronto.diskinlab.org.
UR - http://www.scopus.com/inward/record.url?scp=85049233649&partnerID=8YFLogxK
U2 - 10.1074/mcp.TIR117.000438
DO - 10.1074/mcp.TIR117.000438
M3 - Article
C2 - 29118029
AN - SCOPUS:85049233649
SN - 1535-9476
VL - 17
SP - 1426
EP - 1431
JO - Molecular and Cellular Proteomics
JF - Molecular and Cellular Proteomics
IS - 7
ER -