Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

Keyphrases

• Fibroblast Growth Factor Receptor 3 (FGFR3) 100%
• Achondroplasia 100%
• Thanatophoric Dysplasia 100%
• Dwarfism 42%
• Endochondral Ossification 14%
• Cell Proliferation 14%
• Autosomal Dominant 14%
• Receptor Tyrosine Kinase 14%
• Gene mutation 14%
• Skeletal Disorders 14%
• Extracellular Domain 14%
• Transmembrane Domain 14%
• Tyrosine Phosphorylation 14%
• Missense mutation 14%
• Long Bone 14%
• Ligand-independent 14%
• Neonatal Lethality 14%
• Tyrosine Kinase Domain 14%
• Non-lethal 14%
• Longitudinal Growth 14%
• Continuous Process 14%
• Hypochondroplasia 14%

Biochemistry, Genetics and Molecular Biology

• Dysplasia 100%
• Fibroblast Growth Factor Receptor 3 100%
• Endochondral Ossification 16%
• Autosomal Dominant Inheritance 16%
• Receptor Tyrosine Kinase 16%
• Tyrosine Kinase 16%
• Gene Mutation 16%
• Cell Proliferation 16%
• Tyrosine Phosphorylation 16%
• Transmembrane Domain 16%
• Missense Mutation 16%
• Continuous Process 16%