Gonadal and extragonadal germ cell neoplasia of childhood

Louis P. Dehner

doi:10.1016/S0046-8177(83)80004-5

Gonadal and extragonadal germ cell neoplasia of childhood

Louis P. Dehner

Division of Anatomic and Molecular Pathology (AMP)

Research output: Contribution to journal › Article › peer-review

155 Scopus citations

Abstract

Germ cell tumors in children are characterized by diverse clinical, pathologic, and prognostic features. For this reason, it is difficult to generalize about the behavior of these tumors; cases must be evaluated individually, with consideration for the age of the patient at diagnosis, the anatomic site of the tumor and its histologic appearance. Experimental models and cytogenetic studies of teratomatous development have contributed to our basic understanding of the biology of differentiation and tumorigenesis.

Original language	English
Pages (from-to)	493-511
Number of pages	19
Journal	Human Pathology
Volume	14
Issue number	6
DOIs	https://doi.org/10.1016/S0046-8177(83)80004-5
State	Published - Jun 1983

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title = "Gonadal and extragonadal germ cell neoplasia of childhood",

abstract = "Germ cell tumors in children are characterized by diverse clinical, pathologic, and prognostic features. For this reason, it is difficult to generalize about the behavior of these tumors; cases must be evaluated individually, with consideration for the age of the patient at diagnosis, the anatomic site of the tumor and its histologic appearance. Experimental models and cytogenetic studies of teratomatous development have contributed to our basic understanding of the biology of differentiation and tumorigenesis.",

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AB - Germ cell tumors in children are characterized by diverse clinical, pathologic, and prognostic features. For this reason, it is difficult to generalize about the behavior of these tumors; cases must be evaluated individually, with consideration for the age of the patient at diagnosis, the anatomic site of the tumor and its histologic appearance. Experimental models and cytogenetic studies of teratomatous development have contributed to our basic understanding of the biology of differentiation and tumorigenesis.

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Gonadal and extragonadal germ cell neoplasia of childhood

Abstract

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