Gold nanocages with built-in artificial antibodies for label-free plasmonic biosensing

Limei Tian; Keng Ku Liu; Jeremiah J. Morrissey; Naveen Gandra; Evan D. Kharasch; Srikanth Singamaneni

doi:10.1039/c3tb21551b

Gold nanocages with built-in artificial antibodies for label-free plasmonic biosensing

Limei Tian, Keng Ku Liu, Jeremiah J. Morrissey, Naveen Gandra, Evan D. Kharasch, Srikanth Singamaneni

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

We demonstrate that gold nanocages (AuNCs) with built-in artificial antibodies enable the detection of kidney injury biomarker from synthetic urine down to a concentration of 25 ng ml^-1. Molecularly imprinted AuNCs exhibit excellent selectivity against numerous interfering urinary proteins and remarkable stability over a wide range of pH and specific gravity.

Original language	English
Pages (from-to)	167-170
Number of pages	4
Journal	Journal of Materials Chemistry B
Volume	2
Issue number	2
DOIs	https://doi.org/10.1039/c3tb21551b
State	Published - Jan 14 2014

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title = "Gold nanocages with built-in artificial antibodies for label-free plasmonic biosensing",

abstract = "We demonstrate that gold nanocages (AuNCs) with built-in artificial antibodies enable the detection of kidney injury biomarker from synthetic urine down to a concentration of 25 ng ml-1. Molecularly imprinted AuNCs exhibit excellent selectivity against numerous interfering urinary proteins and remarkable stability over a wide range of pH and specific gravity.",

author = "Limei Tian and Liu, {Keng Ku} and Morrissey, {Jeremiah J.} and Naveen Gandra and Kharasch, {Evan D.} and Srikanth Singamaneni",

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AU - Tian, Limei

AU - Liu, Keng Ku

AU - Morrissey, Jeremiah J.

AU - Gandra, Naveen

AU - Kharasch, Evan D.

AU - Singamaneni, Srikanth

PY - 2014/1/14

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N2 - We demonstrate that gold nanocages (AuNCs) with built-in artificial antibodies enable the detection of kidney injury biomarker from synthetic urine down to a concentration of 25 ng ml-1. Molecularly imprinted AuNCs exhibit excellent selectivity against numerous interfering urinary proteins and remarkable stability over a wide range of pH and specific gravity.

AB - We demonstrate that gold nanocages (AuNCs) with built-in artificial antibodies enable the detection of kidney injury biomarker from synthetic urine down to a concentration of 25 ng ml-1. Molecularly imprinted AuNCs exhibit excellent selectivity against numerous interfering urinary proteins and remarkable stability over a wide range of pH and specific gravity.

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DO - 10.1039/c3tb21551b

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SP - 167

EP - 170

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ER -

Gold nanocages with built-in artificial antibodies for label-free plasmonic biosensing

Abstract

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