Glucose is an important metabolite for all living cells and with other simple sugars and related molecules derived from these sugars it provides sources of readily available energy for cells. Sugars also provide basic carbon skeletons for the biosynthesis of other macromolecules. These include proteins, lipids, nucleic acids, and complex storage polysaccharides (glycogen). Furthermore, hexose sugars are building blocks of glycoproteins such as cartilage-specific proteoglycans. In addition to their role as structural components of the cartilage ECM (Fig. 4), proteoglycans also fulfil adhesive and informational functions.
|Title of host publication||Facilitative Glucose Transporters in Articular Chondrocytes|
|Subtitle of host publication||Expression, Distribution and Functional Regulation of GLUT Isoforms by Hypoxia, Hypoxia Mimetics, Growth Factors and Pro-Inflammatory Cytok|
|Editors||Ali Mobasheri, Carolyn Bondy, Kelle Moley, Alexandrina Ferreira Mendes, Susana Carvalho Rosa, Stephen Richardson, Judith Hoyland, Richard Barrett-Jolley, Mehdi Shakibaei|
|Number of pages||4|
|State||Published - 2008|
|Name||Advances in Anatomy Embryology and Cell Biology|