TY - JOUR
T1 - Giant cell lichenoid dermatitis
AU - Gonzalez, Juan G.
AU - Marcus, Morris D.
AU - Santa Cruz, Daniel J.
PY - 1986/1/1
Y1 - 1986/1/1
N2 - A case of drug-induced lichenoid dermatitis with an unusual epidermotropic multinucleated giant cell inflammatory response is reported. The patient is a 52-year-old white woman who is steroid-dependent because of longstanding systemic lupus erythematosus. At the time of presentation of her generalized papulosquamous pruritic eruption, she was taking oral antihypertensive medications (methyldopa and chlorothiazide). After discontinuation of these medications and local treatment with topical corticosteroids, the skin eruption dramatically improved. Microscopically, the skin lesions had a lichenoid inflammatory pattern, with multiple cytoid bodies, multinucleated giant cells, and a mixed chronic inflammatory infiltrate that included lymphocytes, histiocytes, and eosinophils. (J Am Acad Dermatol 15:87-92, 1986.)
AB - A case of drug-induced lichenoid dermatitis with an unusual epidermotropic multinucleated giant cell inflammatory response is reported. The patient is a 52-year-old white woman who is steroid-dependent because of longstanding systemic lupus erythematosus. At the time of presentation of her generalized papulosquamous pruritic eruption, she was taking oral antihypertensive medications (methyldopa and chlorothiazide). After discontinuation of these medications and local treatment with topical corticosteroids, the skin eruption dramatically improved. Microscopically, the skin lesions had a lichenoid inflammatory pattern, with multiple cytoid bodies, multinucleated giant cells, and a mixed chronic inflammatory infiltrate that included lymphocytes, histiocytes, and eosinophils. (J Am Acad Dermatol 15:87-92, 1986.)
UR - http://www.scopus.com/inward/record.url?scp=0022575042&partnerID=8YFLogxK
U2 - 10.1016/S0190-9622(86)70148-5
DO - 10.1016/S0190-9622(86)70148-5
M3 - Article
C2 - 3522673
AN - SCOPUS:0022575042
VL - 15
SP - 87
EP - 92
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 1
ER -