Getting pumped about heart failure

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Heart failure is a clinical syndrome caused by dysregulated calcium handling and abnormal cardiac pumping capacity. Wahlquist et al. (2014) show that upregulation of microRNA-25 impairs calcium handling leading to pump dysfunction and that targeting microRNA-25 using antisense oligonucleotides reverses pump dysfunction and improves survival in mice with heart failure.

Original languageEnglish
Pages (from-to)896-897
Number of pages2
JournalCell metabolism
Volume19
Issue number6
DOIs
StatePublished - Jun 3 2014

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