Getting a grip on DNA recognition: structures of the basic region leucine zipper, and the basic region helix-loop-helix DNA-binding domains

Tom Ellenberger

Research output: Contribution to journalArticlepeer-review

103 Scopus citations

Abstract

The basic region leucine zipper and basic region helix-loop-helix proteins constitute two large families of eukaryotic transcription factors. Recent crystal structures of basic region leucine zipper-DNA and basic region helix-loop-helix-DNA complexes provide the details of these protein-DNA interactions and offer insights into the details of the site-specific recognition of DNA.

Original languageEnglish
Pages (from-to)12-21
Number of pages10
JournalCurrent Opinion in Structural Biology
Volume4
Issue number1
DOIs
StatePublished - 1994

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