Gestational microbiome: Metabolic perturbations and developmental programming

Sophia Han, Charlotte C. Ellberg, Isoken N. Olomu, Arpita K. Vyas

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


A growing body of research suggests that alterations to the human microbiome are associated with disease states, including obesity and diabetes. During pregnancy, these disease states are associated with maternal microbial dysbiosis. This review discusses the current literature regarding the typical maternal and offspring microbiome as well as alterations to the microbiome in the context of obesity, type 2 diabetes mellitus, and gestational diabetes mellitus. Furthermore, this review outlines the proposed mechanisms linking associations between the maternal microbiome in the aforementioned disease states and offspring microbiome. Additionally, this review highlights associations between alterations in offspring microbiome and postnatal health outcomes.

Original languageEnglish
Pages (from-to)R85
Issue number6
StatePublished - Dec 2021


Dive into the research topics of 'Gestational microbiome: Metabolic perturbations and developmental programming'. Together they form a unique fingerprint.

Cite this