Germline sequencing identifies rare variants in finnish subjects with familial germ cell tumors

Keyphrases

• Proband 100%
• Rare Variants 100%
• Germ Cell Tumor 100%
• Germline Genetic Testing 100%
• Autosomal Recessive 33%
• Variant of Interest 33%
• Yolk Sac Tumor 33%
• Inheritance Model 33%
• Somatic mutation 16%
• Cell Proliferation 16%
• Next-generation Sequencing 16%
• Whole Genome Sequencing 16%
• Aberrations 16%
• Neoplasms 16%
• Neonate 16%
• Rare Germline Variants 16%
• Mucin 5AC (MUC5AC) 16%
• Pedigree 16%
• Gene Variants 16%
• Choriocarcinoma 16%
• Ovarian Teratoma 16%
• Potential Genes 16%
• Germline mutation 16%
• Teratoma 16%
• Illumina Sequencing 16%
• Older Adolescents 16%
• Primordial Germ Cells 16%
• Identified Genes 16%
• Embryonal Carcinoma 16%
• Complex Cancer 16%
• Cornelia De Lange Syndrome (CdLS) 16%
• Finland 16%
• Mutation Landscape 16%
• CTNNA3 16%
• Sacrococcygeal Teratoma 16%
• CACNA1B 16%
• CD109 16%
• IKBKB 16%
• HS6ST1 16%
• ANO7 16%
• FRG1 16%
• Pediatric Germ Cell Tumor 16%
• SUPT6H 16%
• DNM2 16%

Biochemistry, Genetics and Molecular Biology

• Germline 100%
• Germ Cell 100%
• Proband 100%
• Teratoma 50%
• Autosomal Recessive Inheritance 33%
• Adolescence 33%
• Somatic Mutation 16%
• Next Generation Sequencing 16%
• Whole Genome Sequencing 16%
• Pedigree 16%
• Germline Mutation 16%
• Illumina Dye Sequencing 16%
• FRG1 16%
• DNM2 16%
• MUC5AC 16%