Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

Uddhav K. Shigdel, Seung Joo Lee, Mathew E. Sowa, Brian R. Bowman, Keith Robison, Minyun Zhou, Khian Hong Pua, Dylan T. Stiles, Joshua A.V. Blodgett, Daniel W. Udwary, Andrew T. Rajczewski, Alan S. Mann, Siavash Mostafavi, Tara Hardy, Sukrat Arya, Zhigang Weng, Michelle Stewart, Kyle Kenyon, Jay P. Morgenstern, Ende PanDaniel C. Gray, Roy M. Pollock, Andrew M. Fry, Richard D. Klausner, Sharon A. Townson, Gregory L. Verdine

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Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology