Genomic analysis of organismal complexity in the multicellular green alga volvox carteri

Simon E. Prochnik; James Umen; Aurora M. Nedelcu; Armin Hallmann; Stephen M. Miller; Ichiro Nishii; Patrick Ferris; Alan Kuo; Therese Mitros; Lillian K. Fritz-Laylin; Uffe Hellsten; Jarrod Chapman; Oleg Simakov; Stefan A. Rensing; Astrid Terry; Jasmyn Pangilinan; Vladimir Kapitonov; Jerzy Jurka; Asaf Salamov; Harris Shapiro; Jeremy Schmutz; Jane Grimwood; Erika Lindquist; Susan Lucas; Igor V. Grigoriev; Rüdiger Schmitt; David Kirk; Daniel S. Rokhsar

doi:10.1126/science.1188800

Genomic analysis of organismal complexity in the multicellular green alga volvox carteri

Simon E. Prochnik, James Umen, Aurora M. Nedelcu, Armin Hallmann, Stephen M. Miller, Ichiro Nishii, Patrick Ferris, Alan Kuo, Therese Mitros, Lillian K. Fritz-Laylin, Uffe Hellsten, Jarrod Chapman, Oleg Simakov, Stefan A. Rensing, Astrid Terry, Jasmyn Pangilinan, Vladimir Kapitonov, Jerzy Jurka, Asaf Salamov, Harris ShapiroJeremy Schmutz, Jane Grimwood, Erika Lindquist, Susan Lucas, Igor V. Grigoriev, Rüdiger Schmitt, David Kirk, Daniel S. Rokhsar

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476 Scopus citations

Abstract

The multicellular green alga Volvox carteri and its morphologically diverse close relatives (the volvocine algae) are well suited for the investigation of the evolution of multicellularity and development. We sequenced the 138-mega-base pair genome of V. carteri and compared its ̃14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii. Despite fundamental differences in organismal complexity and life history, the two species have similar protein-coding potentials and few species-specific protein-coding gene predictions. Volvox is enriched in volvocine-algal-specific proteins, including those associated with an expanded and highly compartmentalized extracellular matrix. Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity.

Original language	English
Pages (from-to)	223-226
Number of pages	4
Journal	Science
Volume	329
Issue number	5988
DOIs	https://doi.org/10.1126/science.1188800
State	Published - Jul 9 2010

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Prochnik, S. E., Umen, J., Nedelcu, A. M., Hallmann, A., Miller, S. M., Nishii, I., Ferris, P., Kuo, A., Mitros, T., Fritz-Laylin, L. K., Hellsten, U., Chapman, J., Simakov, O., Rensing, S. A., Terry, A., Pangilinan, J., Kapitonov, V., Jurka, J., Salamov, A., ... Rokhsar, D. S. (2010). Genomic analysis of organismal complexity in the multicellular green alga volvox carteri. Science, 329(5988), 223-226. https://doi.org/10.1126/science.1188800

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title = "Genomic analysis of organismal complexity in the multicellular green alga volvox carteri",

abstract = "The multicellular green alga Volvox carteri and its morphologically diverse close relatives (the volvocine algae) are well suited for the investigation of the evolution of multicellularity and development. We sequenced the 138-mega-base pair genome of V. carteri and compared its{\~ }14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii. Despite fundamental differences in organismal complexity and life history, the two species have similar protein-coding potentials and few species-specific protein-coding gene predictions. Volvox is enriched in volvocine-algal-specific proteins, including those associated with an expanded and highly compartmentalized extracellular matrix. Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity.",

author = "Prochnik, {Simon E.} and James Umen and Nedelcu, {Aurora M.} and Armin Hallmann and Miller, {Stephen M.} and Ichiro Nishii and Patrick Ferris and Alan Kuo and Therese Mitros and Fritz-Laylin, {Lillian K.} and Uffe Hellsten and Jarrod Chapman and Oleg Simakov and Rensing, {Stefan A.} and Astrid Terry and Jasmyn Pangilinan and Vladimir Kapitonov and Jerzy Jurka and Asaf Salamov and Harris Shapiro and Jeremy Schmutz and Jane Grimwood and Erika Lindquist and Susan Lucas and Grigoriev, {Igor V.} and R{\"u}diger Schmitt and David Kirk and Rokhsar, {Daniel S.}",

year = "2010",

month = jul,

day = "9",

doi = "10.1126/science.1188800",

language = "English",

volume = "329",

pages = "223--226",

journal = "Science",

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Prochnik, SE, Umen, J, Nedelcu, AM, Hallmann, A, Miller, SM, Nishii, I, Ferris, P, Kuo, A, Mitros, T, Fritz-Laylin, LK, Hellsten, U, Chapman, J, Simakov, O, Rensing, SA, Terry, A, Pangilinan, J, Kapitonov, V, Jurka, J, Salamov, A, Shapiro, H, Schmutz, J, Grimwood, J, Lindquist, E, Lucas, S, Grigoriev, IV, Schmitt, R, Kirk, D & Rokhsar, DS 2010, 'Genomic analysis of organismal complexity in the multicellular green alga volvox carteri', Science, vol. 329, no. 5988, pp. 223-226. https://doi.org/10.1126/science.1188800

TY - JOUR

T1 - Genomic analysis of organismal complexity in the multicellular green alga volvox carteri

AU - Prochnik, Simon E.

AU - Umen, James

AU - Nedelcu, Aurora M.

AU - Hallmann, Armin

AU - Miller, Stephen M.

AU - Nishii, Ichiro

AU - Ferris, Patrick

AU - Kuo, Alan

AU - Mitros, Therese

AU - Fritz-Laylin, Lillian K.

AU - Hellsten, Uffe

AU - Chapman, Jarrod

AU - Simakov, Oleg

AU - Rensing, Stefan A.

AU - Terry, Astrid

AU - Pangilinan, Jasmyn

AU - Kapitonov, Vladimir

AU - Jurka, Jerzy

AU - Salamov, Asaf

AU - Shapiro, Harris

AU - Schmutz, Jeremy

AU - Grimwood, Jane

AU - Lindquist, Erika

AU - Lucas, Susan

AU - Grigoriev, Igor V.

AU - Schmitt, Rüdiger

AU - Kirk, David

AU - Rokhsar, Daniel S.

PY - 2010/7/9

Y1 - 2010/7/9

N2 - The multicellular green alga Volvox carteri and its morphologically diverse close relatives (the volvocine algae) are well suited for the investigation of the evolution of multicellularity and development. We sequenced the 138-mega-base pair genome of V. carteri and compared its ̃14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii. Despite fundamental differences in organismal complexity and life history, the two species have similar protein-coding potentials and few species-specific protein-coding gene predictions. Volvox is enriched in volvocine-algal-specific proteins, including those associated with an expanded and highly compartmentalized extracellular matrix. Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity.

AB - The multicellular green alga Volvox carteri and its morphologically diverse close relatives (the volvocine algae) are well suited for the investigation of the evolution of multicellularity and development. We sequenced the 138-mega-base pair genome of V. carteri and compared its ̃14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii. Despite fundamental differences in organismal complexity and life history, the two species have similar protein-coding potentials and few species-specific protein-coding gene predictions. Volvox is enriched in volvocine-algal-specific proteins, including those associated with an expanded and highly compartmentalized extracellular matrix. Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity.

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DO - 10.1126/science.1188800

M3 - Article

C2 - 20616280

AN - SCOPUS:77954606278

SN - 0036-8075

VL - 329

SP - 223

EP - 226

JO - Science

JF - Science

IS - 5988

ER -

Genomic analysis of organismal complexity in the multicellular green alga volvox carteri

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