Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies disease-specific epimutations on common pathways

Keyphrases

• 450K Array 20%
• Adenoma 60%
• Biological Processes 20%
• Colon Adenocarcinoma 20%
• Colon mucosa 20%
• Colorectal Laterally Spreading Tumors 100%
• Common Pathway 100%
• Common Target 20%
• CpG Island 20%
• Differentially Methylated Probes 60%
• Differentially Methylated Regions 60%
• Disease-specific 100%
• DNA Methylation (DNAm) 20%
• Epigenetic Signature 20%
• Epigenetics 40%
• Epimutation 100%
• Genome-wide DNA Methylation Profiling 100%
• Histone Modification 20%
• Hypermethylated 20%
• Hypomethylating Agents 60%
• Illumina 20%
• Insults 20%
• Intergenic Region 60%
• Laterally Spreading Tumor 100%
• Level Analysis 20%
• Malignancy 20%
• Methylation 20%
• PI3K-Akt Pathway 20%
• Precancerous Conditions 20%
• Rap1 Signaling Pathway 20%
• Ras Signaling 20%
• Regulatory Elements 20%
• Validation Cohort 20%

Biochemistry, Genetics and Molecular Biology

• Biological Phenomena and Functions Concerning the Entire Organism 33%
• Colon 33%
• Colon Mucosa 33%
• CpG Island 33%
• Differentially Methylated Regions 66%
• DNA Methylation 100%
• Epigenetics 100%
• Epimutation 100%
• Histone Modification 33%
• Methylation 33%
• Rap1 33%
• Regulatory Element 33%
• Signal Transduction 33%
• Transcription 33%