Genetic validation of Trypanosoma brucei glutathione synthetase as an essential enzyme

Keyphrases

• Essential Enzymes 100%
• Trypanosoma Brucei 100%
• Genetic Validation 100%
• Glutathione Synthetase 100%
• Trypanothione 83%
• Glutathione 50%
• Biosynthetic Enzymes 33%
• Spermidine 33%
• Late-onset 16%
• Recombinant 16%
• Reduced Expression 16%
• Cell Death 16%
• Homeostasis 16%
• Drug Target 16%
• Decreased Expression 16%
• Fluorescence-activated Cell Sorter 16%
• Two-branch 16%
• Enzyme Expression 16%
• Biosynthetic Pathway 16%
• Conjugation 16%
• Polyamines 16%
• Trypanosomatid Parasites 16%
• Cell Growth Arrest 16%
• Human African Trypanosomiasis 16%
• Eflornithine 16%
• Vector-borne Disease 16%
• Knockout Strategies 16%
• Exogenous Glutathione 16%
• Redox Cofactor 16%
• Polyamine Spermidine 16%
• Polyamine Biosynthesis 16%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Genetics 100%
• Trypanosoma Brucei 100%
• Glutathione Synthase 100%
• Glutathione Synthetase 100%
• Trypanothione 83%
• Glutathione 66%
• Anabolism 33%
• Cell Growth 16%
• Homeostasis 16%
• Cell Death 16%
• Fluorescence Activated Cell Sorting 16%
• Trypanosomatidae 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Trypanosoma Brucei 100%
• Glutathione Synthase 100%
• Trypanothione 83%
• Glutathione 66%
• Polyamine 50%
• Spermidine 50%
• Disease 33%
• Fluorescence Activated Cell Sorting 16%
• Growth Disorder 16%
• Eflornithine 16%
• African Trypanosomiasis 16%
• Trypanosomatidae 16%