@article{0a3d0900cd6a40ae965184596bc9a0e4,
title = "Genetic studies of pathological gambling: A review of methodology and analyses of data from the Vietnam era twin registry",
abstract = "Twin studies represent an important and powerful approach to estimating the relative contributions of environmental and genetic factors to the expression of psychiatric illnesses. In this article, we first explain the rationale for using large populations of monozygotic and dizygotic twin pairs to estimate genetic and environmental contributions to a disorder and the statistical modeling associated with this approach. We then review results from studies of the Vietnam Era Twin Registry that use this methodology to examine the etiology of pathological gambling (PG) behaviors. The results provide strong evidence for genetic contributions to the development of PG in men and set the foundation for future studies aimed at identifying the manner in which specific genes and environmental factors individually and in conjunction contribute to PG.",
keywords = "Addiction, Gambling, Genetics, Methodology, Psychiatric, Twins",
author = "Shah, {Kamini R.} and Eisen, {Seth A.} and Hong Xian and Potenza, {Marc N.}",
note = "Funding Information: Supported by NIH grants DA04604, MH60426 and DA00366 and the United States Department of Veterans Affairs. Numerous organi- zations have provided support for the research described in this manuscript, including: Department of Defense; National Personnel Records Center, National Archives and Records Administration; the Internal Revenue Service; National Opinion Research Center; National Research Council, National Academy of Sciences; the Institute for Survey Research, Temple University. Most importantly, the authors gratefully acknowledge the continued cooperation and participation of the members of the Vietnam Era Twin Registry and their families. Without their contribution this manuscript would not have been possible. Thanks also to Jeffrey F. Scherrer for assistance with the manuscript.",
year = "2005",
month = jun,
doi = "10.1007/s10899-005-3031-x",
language = "English",
volume = "21",
pages = "179--203",
journal = "Journal of Gambling Studies",
issn = "1050-5350",
number = "2",
}