Genetic models for the natural history of smoking: evidence for a genetic influence on smoking persistence

A. C. Heath, N. G. Martin

Research output: Contribution to journalArticlepeer-review

198 Scopus citations

Abstract

We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking persistence, accounting for 53% of the variance. This genetic effect on smoking persistence is independent of genetic effects on smoking initiation.

Original languageEnglish
Pages (from-to)19-34
Number of pages16
JournalAddictive Behaviors
Volume18
Issue number1
DOIs
StatePublished - Jan 1 1993

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