TY - JOUR
T1 - Genetic models for the natural history of smoking
T2 - evidence for a genetic influence on smoking persistence
AU - Heath, A. C.
AU - Martin, N. G.
N1 - Funding Information:
Data collection was supported by grants from the Australian National Health and Medical Research Council and the Australian Associated Brewers. Data analysis was supported by ADAMHA Grants DA05588, AA07535 andAA07728. We thank Dr. John Mathews, Dr. John Gibson, Dr. Rosemary Jardine, and Marilyn Olsen for assistance with data collection. Reprint requests should be sent to A. C. Heath, Dept. of Psychiatry, Washington Univ. School of Medicine, Medical School Box 8 134.4940 Audubon Ave., St. Louis, MO 63 110.
PY - 1993
Y1 - 1993
N2 - We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking persistence, accounting for 53% of the variance. This genetic effect on smoking persistence is independent of genetic effects on smoking initiation.
AB - We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking persistence, accounting for 53% of the variance. This genetic effect on smoking persistence is independent of genetic effects on smoking initiation.
UR - http://www.scopus.com/inward/record.url?scp=0027478680&partnerID=8YFLogxK
U2 - 10.1016/0306-4603(93)90005-T
DO - 10.1016/0306-4603(93)90005-T
M3 - Article
C2 - 8465673
AN - SCOPUS:0027478680
SN - 0306-4603
VL - 18
SP - 19
EP - 34
JO - Addictive Behaviors
JF - Addictive Behaviors
IS - 1
ER -