We evaluated 173 patients in the Clinical Investigation of Duchenne Dystrophy study to determine if patients from the same kindred were more alike clinically than patients within the study population as a whole. A high intrafamilial correlation was noted for age‐adjusted muscle strength scores. While noninherited factors could, in part, explain the results, it seems likely that genetic heterogeneity may contribute to the observed similarity within Duchenne dystrophy kindreds.

Original languageEnglish
Pages (from-to)553-555
Number of pages3
JournalAnnals of neurology
Issue number4
StatePublished - Oct 1987


Dive into the research topics of 'Genetic heterogeneity in Duchenne Dystrophy'. Together they form a unique fingerprint.

Cite this