Genetic epidemiology of the mitsuda reaction in leprosy

M. Feitosa; H. Krieger; I. Borecki; B. Beiguelman; D. C. Rao

doi:10.1159/000154322

Genetic epidemiology of the mitsuda reaction in leprosy

M. Feitosa
, H. Krieger
, I. Borecki
, B. Beiguelman
, D. C. Rao

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ²₁ - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ²₃ = 0.07 - 0.0 = 0.07, p > 0.99; χ²₂ = 198.28 - 0.0 = 198.28, p < 0.0001).

Original language	English
Pages (from-to)	32-35
Number of pages	4
Journal	Human heredity
Volume	46
Issue number	1
DOIs	https://doi.org/10.1159/000154322
State	Published - Jan 1996

Keywords

Genetic epidemiology
Leprosy
Mitsuda reaction
Segregation analysis

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title = "Genetic epidemiology of the mitsuda reaction in leprosy",

abstract = "This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).",

keywords = "Genetic epidemiology, Leprosy, Mitsuda reaction, Segregation analysis",

author = "M. Feitosa and H. Krieger and I. Borecki and B. Beiguelman and Rao, \{D. C.\}",

year = "1996",

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T1 - Genetic epidemiology of the mitsuda reaction in leprosy

AU - Feitosa, M.

AU - Krieger, H.

AU - Borecki, I.

AU - Beiguelman, B.

AU - Rao, D. C.

PY - 1996/1

Y1 - 1996/1

N2 - This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).

AB - This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).

KW - Genetic epidemiology

KW - Leprosy

KW - Mitsuda reaction

KW - Segregation analysis

UR - https://www.scopus.com/pages/publications/0030067903

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DO - 10.1159/000154322

M3 - Article

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SN - 0001-5652

VL - 46

SP - 32

EP - 35

JO - Human heredity

JF - Human heredity

IS - 1

ER -

Genetic epidemiology of the mitsuda reaction in leprosy

Abstract

Keywords

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