Genetic epidemiology of the mitsuda reaction in leprosy

M. Feitosa, H. Krieger, I. Borecki, B. Beiguelman, D. C. Rao

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).

Original languageEnglish
Pages (from-to)32-35
Number of pages4
JournalHuman heredity
Volume46
Issue number1
DOIs
StatePublished - Jan 1996

Keywords

  • Genetic epidemiology
  • Leprosy
  • Mitsuda reaction
  • Segregation analysis

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