Genetic epidemiology of the mitsuda reaction in leprosy

M. Feitosa; H. Krieger; I. Borecki; B. Beiguelman; D. C. Rao

doi:10.1159/000154322

Genetic epidemiology of the mitsuda reaction in leprosy

M. Feitosa, H. Krieger, I. Borecki, B. Beiguelman, D. C. Rao

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11 Scopus citations

Abstract

This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ²₁ - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ²₃ = 0.07 - 0.0 = 0.07, p > 0.99; χ²₂ = 198.28 - 0.0 = 198.28, p < 0.0001).

Original language	English
Pages (from-to)	32-35
Number of pages	4
Journal	Human heredity
Volume	46
Issue number	1
DOIs	https://doi.org/10.1159/000154322
State	Published - Jan 1996

Keywords

Genetic epidemiology
Leprosy
Mitsuda reaction
Segregation analysis

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title = "Genetic epidemiology of the mitsuda reaction in leprosy",

abstract = "This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).",

keywords = "Genetic epidemiology, Leprosy, Mitsuda reaction, Segregation analysis",

author = "M. Feitosa and H. Krieger and I. Borecki and B. Beiguelman and Rao, {D. C.}",

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AU - Feitosa, M.

AU - Krieger, H.

AU - Borecki, I.

AU - Beiguelman, B.

AU - Rao, D. C.

PY - 1996/1

Y1 - 1996/1

N2 - This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).

AB - This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 - 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 = 0.07 - 0.0 = 0.07, p > 0.99; χ22 = 198.28 - 0.0 = 198.28, p < 0.0001).

KW - Genetic epidemiology

KW - Leprosy

KW - Mitsuda reaction

KW - Segregation analysis

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DO - 10.1159/000154322

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VL - 46

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JO - Human heredity

JF - Human heredity

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Genetic epidemiology of the mitsuda reaction in leprosy

Abstract

Keywords

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