Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds

Keyphrases

• Mesenchymal Stem Cells 100%
• Genetic Engineering 100%
• 3D Weaving 100%
• Matrix Deposition 100%
• Woven Scaffolds 100%
• Differential Matrix 100%
• Knockdown 66%
• Glycosaminoglycans 66%
• Cartilage 66%
• Type II Collagen 66%
• Runt-related Transcription Factor 2 (Runx2) 66%
• Polycaprolactone 66%
• Osteochondral Defect 66%
• Multiple Tissues 33%
• Overexpressing 33%
• Transforming Growth Factor-β 33%
• Alkaline Phosphatase Activity 33%
• Skeletal muscle Tissue 33%
• Osteogenic Differentiation 33%
• Chondrogenic 33%
• Chondrogenic Differentiation 33%
• Extracellular Matrix 33%
• Stem Cells 33%
• Synergistic Effect 33%
• Progenitor Cells 33%
• Chondral Defect 33%
• Tissue Engineering 33%
• Culture Conditions 33%
• Local Environment 33%
• Engineering Approach 33%
• Human Mesenchymal Stem Cells (hMSCs) 33%
• Mineral Matrix 33%
• Mineral Deposition 33%
• Bioresorbable Scaffold 33%
• Matrix Production 33%
• Bone-like 33%
• Tissue Reconstruction 33%
• Cartilaginous Matrix 33%
• Differential Induction 33%
• Single Culture 33%

Engineering

• Engineering 100%
• Mesenchymal Stem Cell 100%
• Biochemicals 50%
• Caprolactone 50%
• Osteochondral Defect 50%
• Glycosaminoglycan 50%
• Culture Condition 25%
• Biomaterial Scaffold 25%
• Mineralisation 25%
• Progenitor Cell 25%
• Synergistic Effect 25%
• Stem Cell 25%
• Chondral Defect 25%
• Chondrogenic Differentiation 25%
• Osteogenic Differentiation 25%
• Tissue Regeneration 25%

Biochemistry, Genetics and Molecular Biology

• Stem Cell 100%
• Genetic Engineering 100%
• Type II Collagen 50%
• RUNX2 50%
• Glycosaminoglycan 50%
• Mineralization 25%
• Alkaline Phosphatase 25%
• Progenitor Cell 25%
• Cell Culture 25%
• Tissue Regeneration 25%
• Bone Marrow-Derived Mesenchymal Stem Cells 25%
• Cancer Growth Factor 25%