Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations

Medicine & Life Sciences

• Genetic Variation 67%
• Maintenance 48%
• Metabolic Syndrome 47%
• Diet 47%
• Quantitative Trait Loci 43%
• Population 27%
• Genotype 24%
• Genomic Imprinting 24%
• Fat-Restricted Diet 22%
• Inbred Strains Mice 21%
• Multifactorial Inheritance 21%
• Phenotype 20%
• Precision Medicine 18%
• High Fat Diet 17%
• Dyslipidemias 16%
• Obesity 12%
• Animals 8%
• Genes 6%

Agriculture & Biology

• metabolic syndrome 56%
• genetic variation 43%
• loci 42%
• gender 42%
• genomic imprinting 34%
• diet 28%
• dominance (genetics) 27%
• quantitative trait loci 24%
• precision medicine 22%
• overdominance 18%
• phenotype 18%
• low fat diet 17%
• hyperlipidemia 17%
• genotype 16%
• high fat diet 14%
• diabetes 14%
• obesity 14%
• genetic polymorphism 10%
• mice 8%
• animals 5%
• genes 4%

Earth & Environmental Sciences

• genetic effect 100%
• genetic variation 83%
• diet 60%
• imprinting 34%
• genotype 25%
• phenotype 25%
• fat 23%
• obesity 15%
• diabetes 14%
• polymorphism 12%
• medicine 11%
• additive 10%
• society 8%
• gene 8%
• family 8%
• animal 7%
• effect 5%