Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency

Keyphrases

• Common Variable Immune Deficiency 100%
• IgA Deficiency 100%
• MHC Haplotypes 100%
• B Cells 75%
• Immune Deficiency 75%
• T Cells 50%
• Non-associated 25%
• Autosomal Dominant 25%
• Family Members 25%
• Heat Shock Protein 70 (HSP70) 25%
• Disease-associated 25%
• Environmental Triggers 25%
• Neutral Amino Acid 25%
• Immunodeficiency 25%
• T Helper 25%
• Aged 80 Years and over 25%
• Lymphoproliferative Disorders 25%
• HLA-DQB1 25%
• Disease Expression 25%
• Incomplete Penetrance 25%
• Small Segment 25%
• T-cell Lymphoproliferative Disorder 25%
• HLA-DR3 25%

Immunology and Microbiology

• Haplotype 100%
• Common Variable Immunodeficiency 100%
• Immunoglobulin A Deficiency 100%
• T Cell 60%
• B Cell 60%
• Intravenous Immunoglobulin 40%
• Immunoglobulin M 40%
• Lymphoproliferative Disorders 40%
• Immunodeficiency 40%
• Immunodeficiency 40%
• Tumor Necrosis Factor 20%
• Normal Human 20%
• Autosomal Dominant Inheritance 20%
• Penetrance 20%
• C4A 20%
• Dominant Inheritance 20%
• HLA DQB1 Antigen 20%