Carrot-Zhang and colleagues describe associations between Native American ancestry and the somatic mutational landscape in lung cancer, including tumor mutation burden and specific driver mutations in EGFR, KRAS, and STK11. Local ancestry analysis suggests that specific germline loci, and not environment, underlie these associations.

Original languageEnglish
Pages (from-to)534-536
Number of pages3
JournalCancer discovery
Issue number3
StatePublished - Mar 2021


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