TY - JOUR
T1 - Genetic analysis of drinking behavior in World War II veteran twins
AU - Carmelli, Dorit
AU - Heath, Andrew C.
AU - Robinette, Dennis
PY - 1993
Y1 - 1993
N2 - The objective of the present study was to investigate longitudinal changes in drinking behaviors of adult male twins and model these changes as a function of genetic and environmental influences. Alcohol data available for World War II veteran twins, first surveyed in 1967–69 and followed up during 1983–85, were used to examine components of variability in measures of alcohol consumption. Multivariate biometric analyses of these data indicated 1) longitudinal stability of drinking behaviors in this cohort, 2) a significant contribution of genetic factors to the observed stability that accounted for more than 80% of the stable variation in frequency and in quantity of alcohol consumed per drinking occasion, and 3) evidence for a significant contribution of shared environmental influences to drinking of specific beverages (e.g., wine). The implications of these results for issues of health in the elderly are considered. © 1993 Wiley‐Liss, Inc.
AB - The objective of the present study was to investigate longitudinal changes in drinking behaviors of adult male twins and model these changes as a function of genetic and environmental influences. Alcohol data available for World War II veteran twins, first surveyed in 1967–69 and followed up during 1983–85, were used to examine components of variability in measures of alcohol consumption. Multivariate biometric analyses of these data indicated 1) longitudinal stability of drinking behaviors in this cohort, 2) a significant contribution of genetic factors to the observed stability that accounted for more than 80% of the stable variation in frequency and in quantity of alcohol consumed per drinking occasion, and 3) evidence for a significant contribution of shared environmental influences to drinking of specific beverages (e.g., wine). The implications of these results for issues of health in the elderly are considered. © 1993 Wiley‐Liss, Inc.
KW - alcohol use
KW - longitudinal analysis
KW - male twins
UR - http://www.scopus.com/inward/record.url?scp=0027259295&partnerID=8YFLogxK
U2 - 10.1002/gepi.1370100306
DO - 10.1002/gepi.1370100306
M3 - Article
C2 - 8349101
AN - SCOPUS:0027259295
SN - 0741-0395
VL - 10
SP - 201
EP - 213
JO - Genetic Epidemiology
JF - Genetic Epidemiology
IS - 3
ER -