General mechanism of actomyosin contractility

Nilushi L. Dasanayake; Paul J. Michalski; Anders E. Carlsson

doi:10.1103/PhysRevLett.107.118101

General mechanism of actomyosin contractility

Nilushi L. Dasanayake, Paul J. Michalski, Anders E. Carlsson

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Abstract

Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.

Original language	English
Article number	118101
Journal	Physical Review Letters
Volume	107
Issue number	11
DOIs	https://doi.org/10.1103/PhysRevLett.107.118101
State	Published - Sep 8 2011

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title = "General mechanism of actomyosin contractility",

abstract = "Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.",

author = "Dasanayake, {Nilushi L.} and Michalski, {Paul J.} and Carlsson, {Anders E.}",

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General mechanism of actomyosin contractility

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