General mechanism of actomyosin contractility

Nilushi L. Dasanayake, Paul J. Michalski, Anders E. Carlsson

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.

Original languageEnglish
Article number118101
JournalPhysical Review Letters
Volume107
Issue number11
DOIs
StatePublished - Sep 8 2011

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