Gene induction in intestinal epithelial cells in response to injury

Research output: Contribution to journalReview article

Abstract

Intestinal epithelial cells in acute infections and in inflammatory bowel disease express a series of genes that are not expressed in health. Among these genes are those for interleukin-8, cyclooxygenase-2, and inducible nitric oxide synthase. The mechanisms by which these genes are induced in infection or in inflammatory bower disease are not known, although many of the induced genes have an NF-κB site in their promoters.

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalCurrent opinion in gastroenterology
Volume14
Issue number2
DOIs
StatePublished - Mar 24 1998

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