Gastroesophageal Reflux Disease (GERD)

Kenneth K. Wang; Juan Reyes Genere

doi:10.1016/B978-0-12-801238-3.65937-8

Gastroesophageal Reflux Disease (GERD)

Kenneth K. Wang, Juan Reyes Genere

Institute of Clinical and Translational Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Gastroesophageal reflux disease is a common medical problem worldwide with very important socioeconomic impact including major effects on quality of life. The basic pathophysiology of GERD is the result of significant backflow of acidic gastric juices into the esophagus that lead to mucosal injury or symptoms. Evaluation of GERD symptoms requires a careful history and physical examination to exclude underlying esophageal, cardiac, or systemic disease. GERD symptoms will often respond to acid suppression medications. Endoscopic and surgical antireflux treatments are effective in select patients for whom medical therapy is insufficient.

Original language	English
Title of host publication	Encyclopedia of Gastroenterology, Second Edition
Publisher	Elsevier
Pages	672-681
Number of pages	10
ISBN (Electronic)	9780128124604
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.65937-8
State	Published - Jan 1 2019

Keywords

Antireflux surgery
Atypical GERD
Barrett's Esophagus
Esophageal cancer
Esophagitis
Esophagogastroduodenoscopy
Gastroesophageal junction
Gastroesophageal reflux
Heartburn
Hiatal hernia
Histamine-2 receptor antagonist
Lower esophageal sphincter
Nissen fundoplication
Proton pump inhibitor
Typical GERD

Access to Document

10.1016/B978-0-12-801238-3.65937-8

Cite this

@inbook{e827f80c92a1409c948b74144cb3b513,

title = "Gastroesophageal Reflux Disease (GERD)",

abstract = "Gastroesophageal reflux disease is a common medical problem worldwide with very important socioeconomic impact including major effects on quality of life. The basic pathophysiology of GERD is the result of significant backflow of acidic gastric juices into the esophagus that lead to mucosal injury or symptoms. Evaluation of GERD symptoms requires a careful history and physical examination to exclude underlying esophageal, cardiac, or systemic disease. GERD symptoms will often respond to acid suppression medications. Endoscopic and surgical antireflux treatments are effective in select patients for whom medical therapy is insufficient.",

keywords = "Antireflux surgery, Atypical GERD, Barrett's Esophagus, Esophageal cancer, Esophagitis, Esophagogastroduodenoscopy, Gastroesophageal junction, Gastroesophageal reflux, Heartburn, Hiatal hernia, Histamine-2 receptor antagonist, Lower esophageal sphincter, Nissen fundoplication, Proton pump inhibitor, Typical GERD",

author = "Wang, {Kenneth K.} and Genere, {Juan Reyes}",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-801238-3.65937-8",

language = "English",

pages = "672--681",

booktitle = "Encyclopedia of Gastroenterology, Second Edition",

publisher = "Elsevier",

}

TY - CHAP

T1 - Gastroesophageal Reflux Disease (GERD)

AU - Wang, Kenneth K.

AU - Genere, Juan Reyes

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Gastroesophageal reflux disease is a common medical problem worldwide with very important socioeconomic impact including major effects on quality of life. The basic pathophysiology of GERD is the result of significant backflow of acidic gastric juices into the esophagus that lead to mucosal injury or symptoms. Evaluation of GERD symptoms requires a careful history and physical examination to exclude underlying esophageal, cardiac, or systemic disease. GERD symptoms will often respond to acid suppression medications. Endoscopic and surgical antireflux treatments are effective in select patients for whom medical therapy is insufficient.

AB - Gastroesophageal reflux disease is a common medical problem worldwide with very important socioeconomic impact including major effects on quality of life. The basic pathophysiology of GERD is the result of significant backflow of acidic gastric juices into the esophagus that lead to mucosal injury or symptoms. Evaluation of GERD symptoms requires a careful history and physical examination to exclude underlying esophageal, cardiac, or systemic disease. GERD symptoms will often respond to acid suppression medications. Endoscopic and surgical antireflux treatments are effective in select patients for whom medical therapy is insufficient.

KW - Antireflux surgery

KW - Atypical GERD

KW - Barrett's Esophagus

KW - Esophageal cancer

KW - Esophagitis

KW - Esophagogastroduodenoscopy

KW - Gastroesophageal junction

KW - Gastroesophageal reflux

KW - Heartburn

KW - Hiatal hernia

KW - Histamine-2 receptor antagonist

KW - Lower esophageal sphincter

KW - Nissen fundoplication

KW - Proton pump inhibitor

KW - Typical GERD

UR - http://www.scopus.com/inward/record.url?scp=85143559421&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-801238-3.65937-8

DO - 10.1016/B978-0-12-801238-3.65937-8

M3 - Chapter

AN - SCOPUS:85143559421

SP - 672

EP - 681

BT - Encyclopedia of Gastroenterology, Second Edition

PB - Elsevier

ER -

Gastroesophageal Reflux Disease (GERD)

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this