Gallium-68 Prostate-Specific Membrane Antigen PET Imaging

Michael S. Hofman, Amir Iravani

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

The role of gallium-68 (68Ga) prostate-specific membrane antigen (PSMA) PET imaging is evolving and finding its place in the imaging armamentarium for prostate cancer (PCa). Despite the progress of conventional imaging strategies, significant limitations remain, including identification of small-volume disease and assessment of bone. Clinical studies have demonstrated that 68Ga-PSMA is a promising tracer for detection of PCa metastases, even in patients with low prostate-specific antigen. To provide an accurate interpretation of 68Ga-PSMA PET/computed tomography, nuclear medicine specialists and radiologists should be familiar with physiologic 68Ga-PSMA uptake, common variants, patterns of locoregional and distant spread of PCa, and inherent pitfalls.

Original languageEnglish
Pages (from-to)219-234
Number of pages16
JournalPET Clinics
Volume12
Issue number2
DOIs
StatePublished - Apr 1 2017

Keywords

  • Ga-PSMA
  • Ga-PSMA PET
  • PET
  • Prostate cancer
  • Prostate-specific membrane antigen

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