Gadolinium-Enhanced Computed Tomography Angiography in Multi-Detector Row Computed Tomography: Initial Observations

Kyongtae T. Bae, Ronan McDermott, David S. Gierada, Jay P. Heiken, Mark A. Nolte, Naoki Takahashi, Cheng Hong

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Rationale and Objectives. The feasibility of using gadolinium contrast medium for computed tomography angiography (CTA) in multi-detector row computed tomography and the effect of contrast medium dilution was investigated. Materials and Methods. Three pigs were each scanned in multiple sessions with injections of non-dilute and dilute contrast medium at a dose of 0.3 mmol/kg body weight. Non-spiral dynamic scanning at a fixed mid-abdominal aortic level and thoracoabdominal CTA were performed. Results. The magnitude of peak aortic enhancement was not significantly different between dilute and non-dilute contrast medium injections (P = .88), but the former showed earlier enhancement (mean of 2.3 seconds sooner, P < .01) than the latter. CT angiography with gadolinium contrast medium showed much lower enhancement than iodine contrast medium, but small vessels were readily identifiable. Conclusion. Gadolinium contrast medium combined with multi-detector row computed tomography may provide clinically useful CTA. Dilution of contrast medium shortens the enhancement time but has little effect on the magnitude.

Original languageEnglish
Pages (from-to)61-68
Number of pages8
JournalAcademic radiology
Issue number1
StatePublished - Jan 2004


  • Aorta
  • Computed tomography
  • Contrast media
  • Gadolinium
  • Helical technology
  • Iodine


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