Further development in anatomically constrained MR image reconstruction: Application to multimodal imaging of mouse stroke

Justin P. Haldar, Tzy Haw Wu, Qing Wang, Chin I. Chen, Sheng Kwei Song, Zhi Pei Liang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

MR imaging can leverage a wide variety of intrinsic contrast mechanisms to provide detailed information regarding the anatomy, function, physiology, and metabolism of biological tissues. However, because of low sensitivity, many experiments that reveal higher-order structure and function have been limited due to inherent trade-offs between data acquisition time, signal-to-noise ratio, and resolution. This paper describes the further development of a statistical framework for MR image reconstruction which helps to mitigate these effects. Specifically, we advocate the collection of high-resolution multi-modal MR imaging data, and utilize the correlation between features in these different images to reduce noise while maintaining resolution. The proposed approach is illustrated with joint reconstruction of relaxometry and spectroscopic imaging data in a mouse model of stroke.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages422-425
Number of pages4
StatePublished - Dec 1 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period08/20/0808/25/08

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    Haldar, J. P., Wu, T. H., Wang, Q., Chen, C. I., Song, S. K., & Liang, Z. P. (2008). Further development in anatomically constrained MR image reconstruction: Application to multimodal imaging of mouse stroke. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 422-425). [4649180] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").