Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

D. Hourcade; M. K. Liszewski; M. Krych-Goldberg; J. P. Atkinson

doi:10.1016/S0162-3109(00)80296-9

Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

D. Hourcade, M. K. Liszewski, M. Krych-Goldberg, J. P. Atkinson

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33 Scopus citations

Abstract

The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution. Copyright (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	103-116
Number of pages	14
Journal	Immunopharmacology
Volume	49
Issue number	1-2
DOIs	https://doi.org/10.1016/S0162-3109(00)80296-9
State	Published - 2000

Keywords

CR1 (CD35), MCP (CD46) and DAF (CD55)
Complement regulatory proteins
Functional domains of CR1, MCP, DAF
Pathogen interactions with CR1, MCP, DAF
Regulators of complement (RCA) genes/proteins
Structural variations in mammals of CR1, MCP, DAF

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10.1016/S0162-3109(00)80296-9

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abstract = "The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution. Copyright (C) 2000 Elsevier Science B.V.",

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AU - Atkinson, J. P.

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KW - Functional domains of CR1, MCP, DAF

KW - Pathogen interactions with CR1, MCP, DAF

KW - Regulators of complement (RCA) genes/proteins

KW - Structural variations in mammals of CR1, MCP, DAF

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Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

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Keywords

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