Functional assays to define agonists and antagonists of the sigma-2 receptor

Keyphrases

• Functional Assay 100%
• Sigma-2 Receptor 100%
• Sigma-2 Ligand 100%
• Sigma-2 80%
• Cell Death 40%
• IC50 Value 40%
• Caspase-dependent Apoptosis 40%
• Cell Viability Assay 40%
• Tumor 20%
• Breast Cancer Cell Lines 20%
• Cancer Cells 20%
• Tumor Cell Lines 20%
• Caspase-3 20%
• Cytotoxicity 20%
• Functional Characterization 20%
• Mouse Breast Cancer 20%
• Human Melanoma Cells 20%
• Caspase-3 Activity 20%
• Activity Assay 20%
• Three-class 20%
• MDA-MB-435 20%
• Diverse Structure 20%
• EMT6 20%
• Sigma-2 Receptor Ligands 20%
• Partial Agonist 20%
• Siramesine 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Sigma 2 Opiate Receptor 100%
• Neoplasm 50%
• Caspase 3 50%
• Cell Viability 50%
• Viability Assay 50%
• EC50 50%
• Malignant Neoplasm 25%
• Biological Marker 25%
• Breast Cancer 25%
• Melanoma 25%
• Caspase 25%
• Partial Agonist 25%
• Siramesine 25%
• Cytotoxicity 25%

Immunology and Microbiology

• Agonist 100%
• Caspase 42%
• Cell Death 28%
• EC50 28%
• Cell Viability 28%
• Cancer Cell 14%
• Tumor Cell Line 14%
• Cytotoxicity 14%
• Melanoma Cell Line 14%
• Breast Cancer Cell Line 14%
• Programmed Cell Death 14%