TY - JOUR
T1 - From perception to behavior
T2 - The neural circuits underlying prey hunting in larval zebrafish
AU - Zhu, Shuyu I.
AU - Goodhill, Geoffrey J.
N1 - Funding Information:
This work was supported by the NIH grant R34 NS123913.
Publisher Copyright:
Copyright © 2023 Zhu and Goodhill.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - A key challenge for neural systems is to extract relevant information from the environment and make appropriate behavioral responses. The larval zebrafish offers an exciting opportunity for studying these sensing processes and sensory-motor transformations. Prey hunting is an instinctual behavior of zebrafish that requires the brain to extract and combine different attributes of the sensory input and form appropriate motor outputs. Due to its small size and transparency the larval zebrafish brain allows optical recording of whole-brain activity to reveal the neural mechanisms involved in prey hunting and capture. In this review we discuss how the larval zebrafish brain processes visual information to identify and locate prey, the neural circuits governing the generation of motor commands in response to prey, how hunting behavior can be modulated by internal states and experience, and some outstanding questions for the field.
AB - A key challenge for neural systems is to extract relevant information from the environment and make appropriate behavioral responses. The larval zebrafish offers an exciting opportunity for studying these sensing processes and sensory-motor transformations. Prey hunting is an instinctual behavior of zebrafish that requires the brain to extract and combine different attributes of the sensory input and form appropriate motor outputs. Due to its small size and transparency the larval zebrafish brain allows optical recording of whole-brain activity to reveal the neural mechanisms involved in prey hunting and capture. In this review we discuss how the larval zebrafish brain processes visual information to identify and locate prey, the neural circuits governing the generation of motor commands in response to prey, how hunting behavior can be modulated by internal states and experience, and some outstanding questions for the field.
KW - experience-dependent plasticity
KW - internal states
KW - neural coding
KW - optic tectum
KW - vision
UR - http://www.scopus.com/inward/record.url?scp=85148327497&partnerID=8YFLogxK
U2 - 10.3389/fncir.2023.1087993
DO - 10.3389/fncir.2023.1087993
M3 - Review article
C2 - 36817645
AN - SCOPUS:85148327497
SN - 1662-5110
VL - 17
JO - Frontiers in Neural Circuits
JF - Frontiers in Neural Circuits
M1 - 1087993
ER -