TY - JOUR
T1 - From canines to humans
T2 - Clinical importance of Staphylococcus pseudintermedius
AU - Carroll, Karen C.
AU - Burnham, Carey Ann D.
AU - Westblade, Lars F.
N1 - Publisher Copyright:
© 2021 Carroll et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2021/12
Y1 - 2021/12
N2 - S. pseudintermedius colonizes and infects animals and is a zoonotic pathogen. Infections in canines are primarily SSTIs, and, in many cases, dogs have predisposing factors leading to infection. Human infections are also predominantly SSTIs and often, but not always, with documented canine involvement. The invasive potential of S. pseudintermedius and its complement of virulence factors—many of which mirror those associated with S. aureus—demonstrate this organism has the potential to cause serious disease. β-lactam resistance has emerged as a serious problem for canine health and is typically associated with MDR. Therefore, given the close relationship between canines and humans, S. pseudintermedius is an important candidate for One Health initiatives.
AB - S. pseudintermedius colonizes and infects animals and is a zoonotic pathogen. Infections in canines are primarily SSTIs, and, in many cases, dogs have predisposing factors leading to infection. Human infections are also predominantly SSTIs and often, but not always, with documented canine involvement. The invasive potential of S. pseudintermedius and its complement of virulence factors—many of which mirror those associated with S. aureus—demonstrate this organism has the potential to cause serious disease. β-lactam resistance has emerged as a serious problem for canine health and is typically associated with MDR. Therefore, given the close relationship between canines and humans, S. pseudintermedius is an important candidate for One Health initiatives.
UR - http://www.scopus.com/inward/record.url?scp=85121322937&partnerID=8YFLogxK
U2 - 10.1371/journal.ppat.1009961
DO - 10.1371/journal.ppat.1009961
M3 - Article
C2 - 34855921
AN - SCOPUS:85121322937
SN - 1553-7366
VL - 17
JO - PLoS pathogens
JF - PLoS pathogens
IS - 12
M1 - e1009961
ER -