TY - JOUR
T1 - Frequency-specific mechanism links human brain networks for spatial attention
AU - Daitch, Amy L.
AU - Sharma, Mohit
AU - Roland, Jarod L.
AU - Astafiev, Serguei V.
AU - Bundy, David T.
AU - Gaona, Charles M.
AU - Snyder, Abraham Z.
AU - Shulman, Gordon L.
AU - Leuthardt, Eric C.
AU - Corbetta, Maurizio
PY - 2013/11/26
Y1 - 2013/11/26
N2 - Selective attention allows us to filter out irrelevant information in the environment and focus neural resources on information relevant to our current goals. Functional brain-imaging studies have identified networks of broadly distributed brain regions that are recruited during different attention processes; however, the dynamics by which these networks enable selection are not well understood. Here, we first used functional MRI to localize dorsal and ventral attention networks in human epileptic subjects undergoing seizure monitoring. We subsequently recorded cortical physiology using subdural electrocorticography during a spatialattention task to study network dynamics. Attention networks become selectively phase-modulated at low frequencies (σ,θ) during the same task epochs in which they are recruited in functional MRI. This mechanism may alter the excitability of task-relevant regions or their effective connectivity. Furthermore, different attention processes (holding vs. shifting attention) are associated with synchrony at different frequencies, which may minimize unnecessary cross-talk between separate neuronal processes.
AB - Selective attention allows us to filter out irrelevant information in the environment and focus neural resources on information relevant to our current goals. Functional brain-imaging studies have identified networks of broadly distributed brain regions that are recruited during different attention processes; however, the dynamics by which these networks enable selection are not well understood. Here, we first used functional MRI to localize dorsal and ventral attention networks in human epileptic subjects undergoing seizure monitoring. We subsequently recorded cortical physiology using subdural electrocorticography during a spatialattention task to study network dynamics. Attention networks become selectively phase-modulated at low frequencies (σ,θ) during the same task epochs in which they are recruited in functional MRI. This mechanism may alter the excitability of task-relevant regions or their effective connectivity. Furthermore, different attention processes (holding vs. shifting attention) are associated with synchrony at different frequencies, which may minimize unnecessary cross-talk between separate neuronal processes.
UR - http://www.scopus.com/inward/record.url?scp=84888380051&partnerID=8YFLogxK
U2 - 10.1073/pnas.1307947110
DO - 10.1073/pnas.1307947110
M3 - Article
C2 - 24218604
AN - SCOPUS:84888380051
SN - 0027-8424
VL - 110
SP - 19585
EP - 19590
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 48
ER -