Frequency-specific mechanism links human brain networks for spatial attention

Amy L. Daitch, Mohit Sharma, Jarod L. Roland, Serguei V. Astafiev, David T. Bundy, Charles M. Gaona, Abraham Z. Snyder, Gordon L. Shulman, Eric C. Leuthardt, Maurizio Corbetta

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

Selective attention allows us to filter out irrelevant information in the environment and focus neural resources on information relevant to our current goals. Functional brain-imaging studies have identified networks of broadly distributed brain regions that are recruited during different attention processes; however, the dynamics by which these networks enable selection are not well understood. Here, we first used functional MRI to localize dorsal and ventral attention networks in human epileptic subjects undergoing seizure monitoring. We subsequently recorded cortical physiology using subdural electrocorticography during a spatialattention task to study network dynamics. Attention networks become selectively phase-modulated at low frequencies (σ,θ) during the same task epochs in which they are recruited in functional MRI. This mechanism may alter the excitability of task-relevant regions or their effective connectivity. Furthermore, different attention processes (holding vs. shifting attention) are associated with synchrony at different frequencies, which may minimize unnecessary cross-talk between separate neuronal processes.

Original languageEnglish
Pages (from-to)19585-19590
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume110
Issue number48
DOIs
StatePublished - Nov 26 2013

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