Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas

Wenyin Shi, Varsha Jain, Hyun Kim, Colin Champ, Gaurav Jain, Christopher Farrell, David W. Andrews, Kevin Judy, Haisong Liu, Gregory Artz, Maria Werner-Wasik, James J. Evans

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Purpose Data on the clinical course of irradiated facial nerve schwannomas (FNS) are lacking. We evaluated fractionated stereotactic radiotherapy (FSRT) for FNS. Methods Eight consecutive patients with FNS treated at our institution between 1998 and 2011 were included. Patients were treated with FSRT to a median dose of 50.4 Gy (range: 46.8-54 Gy) in 1.8 or 2.0 Gy fractions. We report the radiographic response, symptom control, and toxicity associated with FSRT for FNS. Results The median follow-up time was 43 months (range: 10-75 months). All patients presented with symptoms including pain, tinnitus, facial asymmetry, diplopia, and hearing loss. The median tumor volume was 1.57 cc. On the most recent follow-up imaging, five patients were noted to have stable tumor size; three patients had a net reduction in tumor volume. Additionally, six patients had improvement in clinical symptoms, one patient had stable clinical findings, and one patient had worsened House-Brackmann grade due to cystic degeneration. Conclusion FSRT treatment of FNS results in excellent control of growth and symptoms with a small rate of radiation toxicity. Given the importance of maintaining facial nerve function, FSRT could be considered as a primary management modality for enlarging or symptomatic FNS.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalJournal of Neurological Surgery, Part B: Skull Base
Volume77
Issue number1
DOIs
StatePublished - Sep 14 2015
Externally publishedYes

Keywords

  • facial nerve schwannoma
  • stereotactic radiotherapy

Fingerprint Dive into the research topics of 'Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas'. Together they form a unique fingerprint.

  • Cite this

    Shi, W., Jain, V., Kim, H., Champ, C., Jain, G., Farrell, C., Andrews, D. W., Judy, K., Liu, H., Artz, G., Werner-Wasik, M., & Evans, J. J. (2015). Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas. Journal of Neurological Surgery, Part B: Skull Base, 77(1), 75-80. https://doi.org/10.1055/s-0035-1564056