@inbook{abde139933204b16bf9c900e6f0356df,
title = "Formulation and Characterization of Antithrombin Perfluorocarbon Nanoparticles",
abstract = "Thrombin, a major protein involved in the clotting cascade by the conversion of inactive fibrinogen to fibrin, plays a crucial role in the development of thrombosis. Antithrombin nanoparticles enable site-specific anticoagulation without increasing bleeding risk. Here we outline the process of making and the characterization of bivalirudin and d-phenylalanyl-l-prolyl-l-arginyl-chloromethyl ketone (PPACK) nanoparticles. Additionally, the characterization of these nanoparticles, including particle size, zeta potential, and quantification of PPACK/bivalirudin loading, is also described.",
keywords = "Anticoagulation, Bivalirudin, PPACK, Perfluorocarbon nanoparticles, Thrombin",
author = "Wilson, {Alexander J.} and Qingyu Zhou and Ian Vargas and Rohun Palekar and Ryan Grabau and Hua Pan and Wickline, {Samuel A.}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media, LLC, part of Springer Nature 2020.",
year = "2020",
doi = "10.1007/978-1-0716-0319-2_8",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "111--120",
booktitle = "Methods in Molecular Biology",
}