Fomepizole should be used more liberally in paracetamol overdose

Ari B. Filip; Michael E. Mullins

doi:10.1111/bcp.15594

Fomepizole should be used more liberally in paracetamol overdose

Research output: Contribution to journal › Article › peer-review

Abstract

Growing clinical and basic science data support the use of fomepizole as an adjunct to N-acetylcysteine in paracetamol poisoning. This safe antidote may be helpful in severely poisoned patients.

Original language	English
Pages (from-to)	594-598
Number of pages	5
Journal	British Journal of Clinical Pharmacology
Volume	89
Issue number	2
DOIs	https://doi.org/10.1111/bcp.15594
State	Published - Feb 2023

Keywords

antidote
commentary
fomepizole
hepatotoxicity
mitochondria
paracetamol

Access to Document

10.1111/bcp.15594

Cite this

@article{e8b605d095684ac4a7d940b1fd1f7b9d,

title = "Fomepizole should be used more liberally in paracetamol overdose",

abstract = "Growing clinical and basic science data support the use of fomepizole as an adjunct to N-acetylcysteine in paracetamol poisoning. This safe antidote may be helpful in severely poisoned patients.",

keywords = "antidote, commentary, fomepizole, hepatotoxicity, mitochondria, paracetamol",

author = "Filip, {Ari B.} and Mullins, {Michael E.}",

note = "Publisher Copyright: {\textcopyright} 2022 British Pharmacological Society.",

year = "2023",

month = feb,

doi = "10.1111/bcp.15594",

language = "English",

volume = "89",

pages = "594--598",

journal = "British Journal of Clinical Pharmacology",

issn = "0306-5251",

number = "2",

}

TY - JOUR

T1 - Fomepizole should be used more liberally in paracetamol overdose

AU - Filip, Ari B.

AU - Mullins, Michael E.

PY - 2023/2

Y1 - 2023/2

N2 - Growing clinical and basic science data support the use of fomepizole as an adjunct to N-acetylcysteine in paracetamol poisoning. This safe antidote may be helpful in severely poisoned patients.

AB - Growing clinical and basic science data support the use of fomepizole as an adjunct to N-acetylcysteine in paracetamol poisoning. This safe antidote may be helpful in severely poisoned patients.

KW - antidote

KW - commentary

KW - fomepizole

KW - hepatotoxicity

KW - mitochondria

KW - paracetamol

UR - http://www.scopus.com/inward/record.url?scp=85143975938&partnerID=8YFLogxK

U2 - 10.1111/bcp.15594

DO - 10.1111/bcp.15594

M3 - Article

C2 - 36471569

AN - SCOPUS:85143975938

SN - 0306-5251

VL - 89

SP - 594

EP - 598

JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

IS - 2

ER -

Fomepizole should be used more liberally in paracetamol overdose

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this