Follow Your Nose: Axon Pathfinding in Olfactory Map Formation

Yao Chen; John G. Flanagan

doi:10.1016/j.cell.2006.11.017

Follow Your Nose: Axon Pathfinding in Olfactory Map Formation

Yao Chen, John G. Flanagan

Research output: Contribution to journal › Short survey › peer-review

14 Scopus citations

Abstract

Two new studies report how discrete identities of olfactory sensory neurons are converted into a spatial map of axonal connections (Imai et al., 2006; Serizawa et al., 2006). They find that levels of cAMP signals derived from olfactory receptors (ORs) can direct targeting of axons along an axis, and that ORs and neural activity regulate expression of adhesion/guidance molecules in mosaic patterns that can sort axons into discrete locations.

Original language	English
Pages (from-to)	881-884
Number of pages	4
Journal	Cell
Volume	127
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2006.11.017
State	Published - Dec 1 2006

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10.1016/j.cell.2006.11.017

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title = "Follow Your Nose: Axon Pathfinding in Olfactory Map Formation",

abstract = "Two new studies report how discrete identities of olfactory sensory neurons are converted into a spatial map of axonal connections (Imai et al., 2006; Serizawa et al., 2006). They find that levels of cAMP signals derived from olfactory receptors (ORs) can direct targeting of axons along an axis, and that ORs and neural activity regulate expression of adhesion/guidance molecules in mosaic patterns that can sort axons into discrete locations.",

author = "Yao Chen and Flanagan, {John G.}",

year = "2006",

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AU - Flanagan, John G.

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N2 - Two new studies report how discrete identities of olfactory sensory neurons are converted into a spatial map of axonal connections (Imai et al., 2006; Serizawa et al., 2006). They find that levels of cAMP signals derived from olfactory receptors (ORs) can direct targeting of axons along an axis, and that ORs and neural activity regulate expression of adhesion/guidance molecules in mosaic patterns that can sort axons into discrete locations.

AB - Two new studies report how discrete identities of olfactory sensory neurons are converted into a spatial map of axonal connections (Imai et al., 2006; Serizawa et al., 2006). They find that levels of cAMP signals derived from olfactory receptors (ORs) can direct targeting of axons along an axis, and that ORs and neural activity regulate expression of adhesion/guidance molecules in mosaic patterns that can sort axons into discrete locations.

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DO - 10.1016/j.cell.2006.11.017

M3 - Short survey

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AN - SCOPUS:33751243643

SN - 0092-8674

VL - 127

SP - 881

EP - 884

JO - Cell

JF - Cell

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Follow Your Nose: Axon Pathfinding in Olfactory Map Formation

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