Follow Your Nose: Axon Pathfinding in Olfactory Map Formation

Yao Chen, John G. Flanagan

Research output: Contribution to journalShort survey

13 Scopus citations

Abstract

Two new studies report how discrete identities of olfactory sensory neurons are converted into a spatial map of axonal connections (Imai et al., 2006; Serizawa et al., 2006). They find that levels of cAMP signals derived from olfactory receptors (ORs) can direct targeting of axons along an axis, and that ORs and neural activity regulate expression of adhesion/guidance molecules in mosaic patterns that can sort axons into discrete locations.

Original languageEnglish
Pages (from-to)881-884
Number of pages4
JournalCell
Volume127
Issue number5
DOIs
StatePublished - Dec 1 2006
Externally publishedYes

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