Focal cortical dysplasia: Comparison of MRI and FDG-PET

Seung Kwon Kim, Dong Gyu Na, Hong Sik Byun, Sang Eun Kim, Yeon Lim Suh, Joon Young Choi, Hye Kyung Yoon, Bokyung Kim Han

Research output: Contribution to journalArticlepeer-review

76 Scopus citations


Purpose: The purpose of this work was to compare the use of MRI and [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) in the diagnosis of focal conical dysplasia (FCD). Method: Nineteen patients with surgically proven FCD were analyzed retrospectively. MRI was performed in all patients, and FDG-PET was performed in 17 patients. We compared the MR and FDG-PET findings of FCD according to the histologic findings that were classified into three grades. Results: Four cases were classified as Grade 1, 4 cases as Grade II, and 11 cases as Grade III FCD. The lesions were detected on MRI in 9 (82%) of the 11 patients with Grade III FCD and in only 1 (13%) of the 8 patients with Grade I and II FCD. Conical hypometabolism of the lesion was revealed on FDG-PET in 6 (86%) of the 7 patients with Grade I and II FCD and in 9 (90%) of the 10 patients with Grade III FCD. The extent of the conical abnormality was larger on FDG-PET than on MRI in 11 (65%) of the 17 patients. Conclusion: FDG-PET is more useful in delineating the conical abnormality in patients with mild degrees of FCD. The extent of the lesion was larger or similar on FDG-PET compared with that of the MRI.

Original languageEnglish
Pages (from-to)296-302
Number of pages7
JournalJournal of computer assisted tomography
Issue number2
StatePublished - 2000


  • Brain, abnormalities
  • Brain, cortex
  • Brain, diseases
  • Emission computed tomography (PET)
  • Epilepsy
  • Magnetic resonance imaging


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