Fluoroscopy based method to determine heart geometry for functional imaging of cardiac electrical activity

Raja N. Ghanem, Charulatha Ramanathan, Ping Jia, Yoram Rudy

Research output: Contribution to journalConference articlepeer-review

Abstract

A fluoroscopy based method for determining heart surface geometry has been developed and validated in phantom and human studies. Biplane fluoroscopic projections were calibrated independently. The heart contour was segmented in each projection and corresponding contour points were matched using epipolar geometry. Points in 3D were reconstructed from the corresponding contour points using point reconstruction. B-splines were approximated from the reconstructed points and meshed to form the heart surface. The fluoroscopy-reconstructed heart was validated in a phantom and human study by comparison to CT imaging. Mean, minimum, maximum and standard deviation of the absolute distance errors were computed for the fluoroscopy-reconstructed heart relative to the CT heart. The mean absolute distance error for the phantom was 4mm. The mean absolute distance error for the human subject was 10mm. In addition to validating the geometry, we also evaluated in the human subject the feasibility of noninvasive imaging of normal cardiac electrical activity on the fluoroscopy-reconstructed heart by comparing the results to those obtained on the CT heart. Noninvasive images on the fluoroscopy-reconstructed heart showed close correlation with those obtained on the CT heart (CC=0.70).

Original languageEnglish
Pages (from-to)63-68
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5031
DOIs
StatePublished - 2003
EventMedical Imaging 2003: Physiology and Function: Methods, Systems, and Applications - San Diego, CA, United States
Duration: Feb 16 2003Feb 18 2003

Keywords

  • Cardiac arrhythmias
  • Cardiac electrophysiology
  • Cardiac imaging
  • Cardiac mapping
  • Electrocardiographic imaging
  • Epipolar geometry
  • Fluoroscopy

Fingerprint

Dive into the research topics of 'Fluoroscopy based method to determine heart geometry for functional imaging of cardiac electrical activity'. Together they form a unique fingerprint.

Cite this