We currently lack good prognostic indicators for patients with advanced disseminated germ cell tumours (GCT). An analysis of archival tumour samples of forty-nine patients with advanced GCT for flow cytometry derived DNA content suggests an inverse relationship between tumour proliferative activity and patient survival. The great majority of patients with advanced GCT have aneuploid tumour subpopulation. This analysis suggests that the survival of patients with advanced GCT may depend in part on kinetic variables present in the primary tumour.
|Number of pages
|International Journal of Andrology
|Published - 1987