Flagellar assembly in two hundred and fifty easy-to-follow steps

Susan K. Dutcher

doi:10.1016/S0168-9525(00)89123-4

Flagellar assembly in two hundred and fifty easy-to-follow steps

Susan K. Dutcher

Research output: Contribution to journal › Review article › peer-review

181 Scopus citations

Abstract

The eukaryotic flagellum is a complex biochemical machine that moves cells or moves materials over the surface of cells, such as in the mammalian esophagus, oviduct or in protozoa. It is composed of over 250 polypeptides that must be assembled into a number of different structures and each structure must be attached with an exact periodicity along the microtubules. Once the flagellum is assembled, each of the components must act in concert and in three dimensions to produce a complex waveform. This review provides an outline of the composition and function of the different structures found in the flagella of Chlamydomonas.

Original language	English
Pages (from-to)	398-404
Number of pages	7
Journal	Trends in Genetics
Volume	11
Issue number	10
DOIs	https://doi.org/10.1016/S0168-9525(00)89123-4
State	Published - Oct 1995

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10.1016/S0168-9525(00)89123-4

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title = "Flagellar assembly in two hundred and fifty easy-to-follow steps",

abstract = "The eukaryotic flagellum is a complex biochemical machine that moves cells or moves materials over the surface of cells, such as in the mammalian esophagus, oviduct or in protozoa. It is composed of over 250 polypeptides that must be assembled into a number of different structures and each structure must be attached with an exact periodicity along the microtubules. Once the flagellum is assembled, each of the components must act in concert and in three dimensions to produce a complex waveform. This review provides an outline of the composition and function of the different structures found in the flagella of Chlamydomonas.",

author = "Dutcher, {Susan K.}",

note = "Funding Information: I thank the members of my laboratory, in particular Steve King and Dr Gary Storrno for many helpful comments. I thank Eric Putz for help with Fig. 1 and Dr Mary Porter for communicating results before publication. The work was supported by grants from the NIH and the NSF.",

year = "1995",

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AU - Dutcher, Susan K.

N1 - Funding Information: I thank the members of my laboratory, in particular Steve King and Dr Gary Storrno for many helpful comments. I thank Eric Putz for help with Fig. 1 and Dr Mary Porter for communicating results before publication. The work was supported by grants from the NIH and the NSF.

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N2 - The eukaryotic flagellum is a complex biochemical machine that moves cells or moves materials over the surface of cells, such as in the mammalian esophagus, oviduct or in protozoa. It is composed of over 250 polypeptides that must be assembled into a number of different structures and each structure must be attached with an exact periodicity along the microtubules. Once the flagellum is assembled, each of the components must act in concert and in three dimensions to produce a complex waveform. This review provides an outline of the composition and function of the different structures found in the flagella of Chlamydomonas.

AB - The eukaryotic flagellum is a complex biochemical machine that moves cells or moves materials over the surface of cells, such as in the mammalian esophagus, oviduct or in protozoa. It is composed of over 250 polypeptides that must be assembled into a number of different structures and each structure must be attached with an exact periodicity along the microtubules. Once the flagellum is assembled, each of the components must act in concert and in three dimensions to produce a complex waveform. This review provides an outline of the composition and function of the different structures found in the flagella of Chlamydomonas.

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M3 - Review article

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VL - 11

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EP - 404

JO - Trends in Genetics

JF - Trends in Genetics

IS - 10

ER -

Flagellar assembly in two hundred and fifty easy-to-follow steps

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