TY - JOUR
T1 - Fitness, fatness, and estimated coronary heart disease risk
T2 - The HERITAGE Family Study
AU - Katzmarzyk, P. T.
AU - Gagnon, J.
AU - Leon, A. S.
AU - Skinner, J. S.
AU - Wilmore, J. H.
AU - Rao, D. C.
AU - Bouchard, C.
PY - 2001
Y1 - 2001
N2 - Purpose: To determine the contributions of fatness and fitness to the estimated risk of future coronary heart disease (CHD). Methods: The sample consisted of 212 black and 411 white adult sedentary participants. Percent body fat (%BF) was measured using densitometry, whereas maximal oxygen uptake (VO2max) was measured on a cycle ergometer. Risk of future CHD was estimated using the revised Framingham Heart Study algorithm. Results: For fatness, the odds ratios for risk of future CHD were 1.83 and 1.70 for the moderate and high tertiles, respectively, compared with the low tertile. Similarly, the odds ratios for VO2max were 1.29 (NS) and 1.62, for the moderate and low tertiles, respectively. Removing VO2max from the full model had no effect; however, removing %BF resulted in a significantly weaker model (X2 = 10.38, P < 0.01). Conclusion: Both fatness and fitness are important predictors of risk of future CHD, based on the Framingham index.
AB - Purpose: To determine the contributions of fatness and fitness to the estimated risk of future coronary heart disease (CHD). Methods: The sample consisted of 212 black and 411 white adult sedentary participants. Percent body fat (%BF) was measured using densitometry, whereas maximal oxygen uptake (VO2max) was measured on a cycle ergometer. Risk of future CHD was estimated using the revised Framingham Heart Study algorithm. Results: For fatness, the odds ratios for risk of future CHD were 1.83 and 1.70 for the moderate and high tertiles, respectively, compared with the low tertile. Similarly, the odds ratios for VO2max were 1.29 (NS) and 1.62, for the moderate and low tertiles, respectively. Removing VO2max from the full model had no effect; however, removing %BF resulted in a significantly weaker model (X2 = 10.38, P < 0.01). Conclusion: Both fatness and fitness are important predictors of risk of future CHD, based on the Framingham index.
KW - Adipose tissue
KW - Aerobic fitness
KW - Cardiovascular disease
KW - Obesity
KW - Prediction
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=0035057279&partnerID=8YFLogxK
U2 - 10.1097/00005768-200104000-00012
DO - 10.1097/00005768-200104000-00012
M3 - Article
C2 - 11283434
AN - SCOPUS:0035057279
SN - 0195-9131
VL - 33
SP - 585
EP - 590
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 4
ER -