Abstract
(Chemical Equation Presented) An enantiospecific route to the previously unreported 1,6-difunctionalized dodecahydrobenz[f]indene ring system is described. Optically pure Hajos - Parrish ketone is used as the building block for preparation of a 6-methyleneinden-5-ol. This allylic alcohol is then utilized in a Claisen rearrangement under Johnson's conditions to introduce a side chain that is further modified and cyclized to produce the benz[f]indene ring system.
Original language | English |
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Pages (from-to) | 1089-1092 |
Number of pages | 4 |
Journal | Journal of Organic Chemistry |
Volume | 70 |
Issue number | 3 |
DOIs | |
State | Published - Feb 4 2005 |