Finite difference vascular model for 3-D cancer therapy with hyperthermia

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4 Scopus citations

Abstract

A new numerical algorithm for predicting three-dimensional temperature fields in tissue with large vessels is presented. The capabilities of the model were demonstrated by considering a thermally significant countercurrent vessel pair (600 μ in diameter each) embedded in an elemental tissue volume and feeding a tumor under hyperthermia. Tumor-peripheral heating with ultrasound was also considered. Results showed that under conditions representative of those that may be found in the clinic the arterial blood remained under therapeutic levels before entering the tumor volume. Peripheral heating was very effective in raising the temperature of the normal solid tissue surrounding the tumor and in pushing high temperature gradients away from the tumor margin; however, it was not sufficient to heat the arterial blood to therapeutic levels.

Original languageEnglish
Title of host publicationAdvances in Bioheat and Mass Transfer
PublisherPubl by ASME
Pages107-111
Number of pages5
ISBN (Print)079181047X
StatePublished - Dec 1 1993
EventProceedings of the 1993 ASME Winter Annual Meeting - New Orleans, LA, USA
Duration: Nov 28 1993Dec 3 1993

Publication series

NameAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
Volume268
ISSN (Print)0272-5673

Conference

ConferenceProceedings of the 1993 ASME Winter Annual Meeting
CityNew Orleans, LA, USA
Period11/28/9312/3/93

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    Moros, E. G., Straube, W. L., & Myerson, R. J. (1993). Finite difference vascular model for 3-D cancer therapy with hyperthermia. In Advances in Bioheat and Mass Transfer (pp. 107-111). (American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD; Vol. 268). Publ by ASME.