Abstract
IgG4 serology was evaluated for early diagnosis of onchocerciasis in children living within an endemic focus of forest-type onchocerciasis in Nigeria. IgG4 serology proved to be more sensitive than conventional skin snip examination being able to detect 42% of infected children as opposed to 24% by snip examination. Furthermore, age was not a limitation to the technique within the 8 - 12 y spectrum. We conclude that IgG4 serology in children is a reliable indicator of community microfilarial rate and ongoing transmission of onchocerciasis.
| Original language | English |
|---|---|
| Pages (from-to) | 59-61 |
| Number of pages | 3 |
| Journal | Tropical Medicine and Parasitology |
| Volume | 43 |
| Issue number | 1 |
| State | Published - Jan 1 1992 |