Fetal hepatosplenomegaly associated with transient myeloproliferative disorder in trisomy 21

George A. Macones, Anthony Johnson, Denise Tilley, Ronald Wade, Ronald Wapner

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The in utero diagnosis of fetal myeloproliferative disease was made by cordocentesis following the ultrasound appearance of fetal hepatosplenomegaly and mild hydrops. The 2 fetuses reported both had leukocyte counts greater than 75, 000/mm3 with a predominance of blast forms. In both cases the karyotype revealed trisomy 21.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
JournalFetal Diagnosis and Therapy
Volume10
Issue number2
DOIs
StatePublished - 1995

Keywords

  • Down syndrome
  • Hepatosplenomegaly

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